Based on Patrick DeWitt's novel, This movie revolves around the colorfully named gold prospector Hermann Kermit Warm (Riz Ahmed), who's being pursued across one thousand miles of 1850s Oregon desert to San Francisco, California by the notorious assassins Eli Sisters (John C. Reilly) and Charlie Sisters (Joaquin Phoenix). Except Eli is having a personal crisis and beginning to doubt the longevity of his chosen career. And Hermann might have a better offer.