Seymour Krelborn is a nerdy orphan working at Mushnik's, a flower shop in urban Skid Row. He harbors a crush on fellow co-worker Audrey Fulquard, and is berated by Mr. Mushnik daily. One day as Seymour is seeking a new mysterious plant, he finds a very mysterious unidentified plant which he calls Audrey II. The plant seems to have a craving for blood and soon begins to sing for his supper. Soon enough, Seymour feeds Audrey's sadistic dentist boyfriend to the plant and later, Mushnik for witnessing the death of Audrey's ex. Will Audrey II take over the world or will Seymour and Audrey defeat it?