Dr. Herbert Bock (George C. Scott), the chief of medicine in a New York City teaching hospital, is contemplating suicide. He's impotent, his wife has left him, and his children aren't speaking to him. His hospital is also suffering from a recent spate of inexplicable deaths. In the midst of these setbacks, Bock is romantically drawn to the much younger Barbara Drummond (Dame Diana Rigg), whose father is a patient. As Barbara restores Bock's will to live, it turns out that the hospital deaths are murders.